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Szczepanek, Elżbieta
2024
Praca doktorska
We extended knowledge regarding the occurrence of cardiovascular events in patients with chronic myeloid leukemia (CML) treated with tyrosine kinase inhibitors (TKIs) and assessed the function of the vascular endothelium in these patients, particularly in relation to cardiovascular risk factors. Patients with CML who commenced therapy with imatinib in chronic phase achieved long overall survival as well as progression- free and free from late adverse events survival, treatment strategy for ponatinib was presented, takmg mto also in the cardiovascular system. The optimal account the adverse effect of this drug on the function of vascular endothelium. Endothelial function in those patients assessed based on the FMD, FMSF, and RH-PAT tests was mainly related to CML-specific factors, including the duration of TKis treatment and ponatinib rather than to cardiovascular risk based on SCORE2/SCORE2-0P algorithms. FMSF-based assessment of skin microcirculation proved to be a sensitive method for detecting the vascular effects of TKIs.
Kraków
2 - studia doktoranckie
Rada Dyscypliny Nauki medyczne
Sacha, Tomasz
oai:dl.cm-uj.krakow.pl:5188
ZB-141640
pol; eng
tylko w bibliotece
Jan 28, 2025
0
http://149.156.57.56:8080/publication/5189
RDF
OAI-PMH
Gibek, Katarzyna
Pęksa, Jan Wojciech
Studziński, Krzysztof
Waśniowska, Anna
Pacia, Klaudia Krystyna
Walczewska, Jolanta
Nowakowski, Jarosław
Citation style: chicago-author-date iso690-author-date chicago-author-date
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